Kev daws teeb meem tag nrho rau IVD tuam txhab lag luam kom txiav cov nqi raw khoom siab

DMT-dC (Bz)-CE Phosphoramidite (tus qauv) DMT-dG(i-Bu)-CE Phosphoramide (tus qauv) DMT-dG(dmf)-CE Phosphoramidite (ceev cleavage) DMT-dT-CE Phosphoramide DMT-dA(Bz)-CE Phosphoramide

 

Tag nrho lub ntiaj teb no yuav tsum tau nrog cov nqi siab ntawm cov khoom siv raw, thiab nws cuam tshuam rau ntau yam IVD thiab lwm lub tuam txhab hauv kev lag luam no.

Txhawm rau pab nrog txhua tus neeg siv khoom hauv qhov xwm txheej no, HonyaBiotech muaj tag nrho Oligo synthesis voj voog kev daws teeb meem rau IVD feedstock ntau lawm.—HY-12 mid-throughput Synthesizer, customized txhawb siab automated instrumentation, zoo SynthesisAmiditethiab SynthesisReagentsthiab cov kev pabcuam kev tsim khoom puv ntoob.

Hauv 3 lub hlis, qee tus ntawm peb cov neeg siv khoom tsis txaus ntseeg lawv tuaj yeem ua tiav nws tus kheej cov khoom siv IVD, txo cov nqi tsim khoom, thaum tau txais cov txheej txheem tag nrho thiab teb cov txheej txheem tsim khoom txhua lub sijhawm, txuag sijhawm thiab nqi.

 

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Cov kev txwv ntawm solid-phase oligonucleotide synthesis

Txawm hais tias DNA synthesis ua tau zoo, impurities inevitably accumulates.Lub synthesis ntawm 20mer oligodeoxynucleotide koom nrog ntau tshaj 100 tus neeg cov kauj ruam tshuaj, txhua tus muaj peev xwm ua rau tsis xav tau kev tshwm sim.Ntxiv nrog rau qhov tsub zuj zuj ntawm cov khoom ua tsis tiav tshwm sim los ntawm kev sib txuas tsis tiav, qhov kev txiav tawm ntawm cov saw hlau oligonucleotide tom qab depurination kuj tuaj yeem tsim cov ntu kawg.

Kev hloov tshuaj lom neeg ntawm lub hauv paus heterocycles qee zaum tshwm sim, thiab cov khoom hloov pauv oligonucleotide tuaj yeem yog mutagens, uas tuaj yeem ua rau muaj teeb meem loj hauv kev sim tshuaj lom neeg.Vim yog qhov tshwm sim ntawm kev tawm tsam sab nraud, kom tau txais cov purity oligonucleotides siab heev, nws yog ib qho tsim nyog yuav tsum siv txoj hauv kev zoo tshaj plaws rau kev ua kom huv.


Post lub sij hawm: Sep-06-2022